Temporal lobe epilepsy treatment

Temporal Lobe Epilepsy Treatment & Management: Approach Considerations, Antiepileptic

Temporal lobectomy is the definitive treatment for medically intractable temporal lobe epilepsy, as it has a high seizure-free rate. For patients who had mesial temporal lobe epilepsy and disabling seizures for no more than 2 consecutive years following adequate trials of 2 brand-name AEDs, Engel et al found that resective surgery plus AED treatment resulted in a lower probability of seizures. diagnosis is uncertain. TLE is treated with medications, resective surgery, and vagus nerve stimulation. Epilepsy surgery should be considered in all patients with refractory partial epilepsy. [Rev Neurol Dis. 2004;1(1):2-9] © 2004 MedReviews, LLC Key words: Epilepsy • Seizures • Video electroencephalography • Magneti Temporal lobe epilepsy (TLE) is the most common form of focal (partial) epilepsy. It can be hard for people with TLE to become completely seizure free with seizure medicines alone, though medicines may lower the number of seizures. People with drug-resistant medial temporal lobe epilepsy have a higher risk for memory and mood difficulties

Treatments for temporal lobe epilepsy includes medications, diet, surgery, laser, and electrical brain stimulator devices. Medications. Many medications are available to treat people who have temporal lobe seizures What Are the Treatments for Temporal Lobe Seizures? Anticonvulsant medications may help reduce or eliminate recurrent seizures in some people. They include: brivaracetam (Briviact) cannabidio Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes. TLE is the most common form of epilepsy with focal seizures. A focal seizure in the temporal lobe may spread to other areas in the brain when it may become a focal to bilateral seizure

Surgery is another common treatment for people with temporal lobe epilepsy. It's used to eliminate or reduce the number of seizures a person experiences Surgical approaches for mesial temporal lobe epilepsy include open resection and other minimally invasive techniques. Standard open resective surgery is considered to be the most effective and safe treatment option for temporal lobe epilepsy with superiority to prolonged medical therapy in terms of long term outcomes 32) Vitamin B-6 is used to treat a rare form of epilepsy known as pyridoxine-dependent seizures. This type of epilepsy usually develops in the womb or soon after birth

Temporal Lobe Damage Treatment. Treatment for temporal lobe damage will require a personalized plan that targets each individual's unique secondary effects. Because damage to this region of the brain primarily affects cognitive functions like memory and communication, working on cognitive rehabilitation exercises can be effective Although some patients can control their seizures with anti-epileptic medication, temporal lobe epilepsy is a condition that often is amenable to surgery. Because the seizures are localized and have an identifiable source in the brain, the removal of all or part of the temporal lobe, called a temporal lobectomy, often can stop the seizures entirely The Epilepsy of the temporal lobe (ELT) is a type of epilepsy Which originates in the temporal lobes of the brain, important areas in the memory , Language and emotional processing. When the Convulsions , Alterations in these functions may occur. Some of the manifestations are strange feelings like fear or euphoria, déjà vu, Hallucinations ,.

Temporal Lobe Epilepsy Epilepsy Foundatio

Temporal Lobe Epilepsy: Causes, Symptoms, Diagnosis & Treatmen

Temporal Lobe Seizure Diagnosis and Treatment - WebM

Alternative surgical procedures like gamma knife stereotactic radiosurgery and amygdalohippocampal stimulation are currently under assessment, with promising results. Surgical treatment for mesial temporal lobe epilepsy associated with hippocampal sclerosis. Rev Neurol (Paris). 2015 Mar;171(3):315-25.doi: 10.1016/j.neurol.2015.01.561 1. Introduction. Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy [].In medical centers where epilepsy surgery is performed, neuropathologists often encounter temporal lobe resection specimens. Most patients scheduled for surgical resection present with intractable focal epilepsy and are selected for surgery based on clinical, electrophysiology, and neuroimaging criteria Bandt SK, Werner N, Dines J, Rashid S, Eisenman LN, Hogan RE, et al. Trans-middle temporal gyrus selective amygdalohippocampectomy for medically intractable mesial temporal lobe epilepsy in adults: Seizure response rates, complications, and neuropsychological outcomes. Epilepsy Behav. 2013 Jul. 28(1):17-21.

Temporal lobe epilepsy with GAD antibodies (GAD-TLE) is an immune-mediated syndrome. • We evaluate the therapy response to immunotherapies and epilepsy surgery. • Seizure response to immunotherapies in 13 people with GAD-TLE was poor. • GAD-TLE patients respond worse than other people with TLE to epilepsy surgery. Wolf HK, Campos MG, Zentner J, et al. Surgical pathology of temporal lobe epilepsy. Experience with 216 cases. J Neuropathol Exp Neurol 1993; 52:499. Tassi L, Meroni A, Deleo F, et al. Temporal lobe epilepsy: neuropathological and clinical correlations in 243 surgically treated patients. Epileptic Disord 2009; 11:281 Overview. Temporal lobe seizures begin in the temporal lobes of your brain, which process emotions and are important for short-term memory. Some symptoms of a temporal lobe seizure may be related to these functions, including having odd feelings — such as euphoria, deja vu or fear Chapter 13 Temporal lobe epilepsy BEATE DIEHL and JOHN S. DUNCAN UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, and Epilepsy Society, Chalfont St Peter, Buckinghamshire In community studies, the cumulative incidence of non-febrile seizures is about 20 per 1000 Temporal lobe epilepsy is a form of epilepsy that originates in the temporal lobe of the brain. In this lesson we will review the symptoms, treatment, and medications for temporal lobe epilepsy

Temporal lobe epilepsy - Wikipedi

How is temporal lobe epilepsy treated? Deep brain stimulation. Surgery.The goal of surgery is to stop seizures from happening.; Vagus nerve stimulation.A device implanted underneath the skin of your chest stimulates the vagus nerve in your neck, sending signals to your brain that inhibit seizures.. Treatments for temporal lobe epilepsy (TLE) Focal seizures affect only part of the brain. TLE can be difficult to diagnose because the seizures may not show up on an EEG. TLE is usually treated with anti-epileptic medication (AEDs) like other types of epilepsy. Where there is a clear seizure focal point and the perso

1. Introduction. Epilepsy surgery is an effective therapeutic option for patients with focal seizures who do not respond to appropriate treatment with antiepileptic drugs (AEDs) [].Patients with temporal lobe epilepsy (TLE) are the most common surgical candidates ‎This book describes Temporal Lobe Epilepsy, Diagnosis and Treatment and Related Diseases Epilepsy is a brain disorder that induces changes in brain cell activity that lead to seizures, durations of unusual behavior or feelings, and in some patients a loss of consciousness. Temporal Temporal lobe epilepsy is a type of focal epilepsy (where seizures start in one specific area of the brain). The seizures begin in the temporal lobes, which are sections of the brain behind your ears. Your temporal lobes process the things you hear and help build memories. Temporal lobe epilepsy can begin at any time in life, although it most. Temporal lobe epilepsy (TLE) is a highly prevalent syndrome among people with epilepsy, and is usually refractory to drug treatment. Structural and physiological changes, such as hippocampal sclerosis, are often present in TLE patients

Temporal lobe epilepsy, as the name suggests, mainly affects the temporal lobe of the brain. This lobe is located at the bottom of the brain (take a look at the image below for reference). One particular structure within the temporal lobe is called the hippocampus. Its main job is creating memories in the brain but, when something goes wrong, it can often trigger seizures and epilepsy Temporal lobe epilepsy (TLE) can be unresponsive to treatment. Here, the authors show that treatment with D-Serine mitigates TLE and acts on neurons and glia, attenuating neuronal loss and. Overview. Temporal lobe epilepsy (TLE) is a disorder of the nervous system due to unprovoked seizures originating from the temporal lobe. The main cause of TLE is neuronal hyperexcitability due to the presence of pathological changes in the temporal lobe of the brain such as neuronal loss, mutation, granule cell dispersion and malformations of cortical development Initial management of patients with temporal lobe epilepsy is with antiepileptic drugs, but these control seizures in only half the patients. Patients refractory to drugs should be evaluated for resective surgery. That evaluation requires identification of a focus of onset of seizures, as well as establishing that the focus is in an area of the brain that can be removed with a low risk of new. Mesial temporal lobe epilepsy treatment Radiofrequency thermocoagulation. Stereoelectroencephalography guided radiofrequency thermocoagulation.. Radiosurgery. see Mesial temporal lobe epilepsy radiosurgery.. Surgery. see Temporal lobe epilepsy surgery.. Surgical resection is the gold standard treatment for drug-resistant focal epilepsy, including mesial temporal lobe epilepsy (MTLE) and other.

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Temporal lobe epilepsy (TLE) is the most common form of medically intractable epilepsy. Advances in electrophysiology and neuroimaging have led to a more precise localization of the epileptogenic zone within the temporal lobe. Resective surgery is the most effective treatment for TLE. Despite the variability in surgical techniques and in the extent of resection, the overall outcomes of. Familial temporal lobe epilepsy (FTLE) comprises two genetic epilepsy syndromes: autosomal dominant lateral temporal epilepsy (ADLTE; MIM 600512) and familial mesial temporal lobe epilepsy (FMTLE). ADLTE is characterized by focal seizures with auditory or aphasic auras, no brain structural abnormalities, and usually good outcome Temporal lobe epilepsy: Diagnosis & Treatment . 7 Comments. by Dannyelle Kovac — Last updated: 2013-12-26 . in Nervous System Disorders and Diseases. The temporal lobe is located on either side of the brain just above the ear. Introduction. The main symptom of the Temporal lobe epilepsy is brief loss of consciousness Surgical treatment • The most common epilepsy surgery procedure is temporal lobe resection. • The procedures more frequently practiced are standard anterior temporal resection and amygdalo- hippocampectomy. • Several studies report similar success rate with both techniques achieving seizure freedom between 60 and 70%. Lutz et al., 2004 78

Temporal lobe epilepsy: Surgical treatment.pdf. Content uploaded by Carlos Campos. Author content. All content in this area was uploaded by Carlos Campos on Nov 11, 2015 . Content may be subject. Community research on temporal lobe epilepsy. Treatments, triggers & symptoms, from the experiences of 162 diagnosed members. Connect and contribute to the research Temporal lobe epilepsy is considered to be one of the most common types of epilepsy. Structures that constitute the mesial temporal lobe, primarily hippocampus, are hypothesized to be the origin of excitatory signals. Cognition, memory and functional ability are all impaired as a result of seizure activity. Imaging studies and EEG confirm the diagnosis, whereas treatment is primarily surgical.

Temporal Lobe Epilepsy: Causes, Symptoms, and Treatmen

Surgical Treatment for Mesial Temporal Lobe Epilepsy in

Surgery for temporal-lobe epilepsy Review Our current knowledge of mesial-temporal-lobe epilepsy (MTLE) is extensive, yet still insufficient to draw final conclusions on the optimal approach to its therapy. MTLE has been well characterised and can usually be identified with noninvasive studies including scalp electroencephalo Mesial temporal lobe epilepsy. Temporal lobe epilepsy (TLE) is a chronic neurological condition characterized by recurrent seizures (epilepsy) which originate in the temporal lobe of the brain with progressive neurological disabilities, including cognitive deficit, anxiety and depression.. The seizures involve sensory changes, for example smelling an unusual odour that is not there, and. Mesial temporal lobe epilepsy (MTLE) is often discussed as a separate entity because it is quite distinct from its lateral counterpart in terms of etiology, semiology, imaging, and electrophysiologic characteristics. Moreover, the mesial temporal lobes tend to be the site of origin of close to 80% of all TLEs. [4 Seizure onset patterns in the pilocarpine model of mesial temporal lobe epilepsy are associated to the activity of distinct neuronal networks. A: Representative example of a hypersynchronous-onset (HYP) seizure recorded in a pilocarpine-treated animal. Note the periodic focal pre-ictal spikes (asterisks) before seizure onset in CA3 and subiculum temporal lobe epilepsy - the most common epilepsy syndrome with focal seizures. temporal lobe resection - a type of surgery for temporal lobe epilepsy in which all or part of the affected temporal lobe of the brain is removed. tonic seizures - seizures that cause stiffening of muscles of the body, generally those in the back, legs, and arms

Results: One intention-to-treat Class I randomized, controlled trial of surgery for mesial temporal lobe epilepsy found that 58% of patients randomized to be evaluated for surgical therapy (64% of those who received surgery) were free of disablin Focal epilepsies include idiopathic location-related epilepsies (ILRE), frontal lobe epilepsy, temporal lobe epilepsy, parietal lobe epilepsy and occipital lobe epilepsy. Focal epilepsy may be treated with medication, and occasionally with diet, nerve stimulation or surgery, especially if the condition is due to a scar or other lesion in the brain

Temporal lobe epilepsy causes, symptoms, diagnosis, treatment & prognosi

5 Natural Treatments for Epilepsy - Healthlin

Dr. Igor Yusupov answered. Yes and No: Temporal lobe epilepsy is a specific disease that may be helped by temporal lobe resection. It may be easier to diagnose and offer treatment but the t.. May 12, 2019 - Explore c fm's board Temporal Lobe Epilepsy on Pinterest. See more ideas about temporal lobe epilepsy, epilepsy, epilepsy awareness Temporal lobe epi: Many people with temporal lobe epilepsy have partial onset seizures or complex partial seizures. Many people with this condition can be successfully treated with medication, such as lamotrigine or levetiracetam

Temporal lobes. If you have been diagnosed with temporal lobe epilepsy (TLE) it means you have seizures starting in one or other of the temporal lobes. Seizures starting in the temporal lobes are usually focal impaired awareness seizures, but focal aware seizures can also happen Apr 14, 2015 - Explore Carolyn Mitchell's board Temporal Lobe Seizures, followed by 3192 people on Pinterest. See more ideas about seizures, temporal lobe epilepsy, epilepsy Symptoms And Treatment Of Epilepsy 1275 Words | 6 Pages. Seizures There are many chronic conditions that can affect people today with one such condition being epilepsy. This disease does not only affect a person physiologically but also affects how they interact with others, perform activities of daily living and the basic needs of a person, such as, driving or maintaining a job Surgery of refractory temporal lobe epilepsy — the only treatment modality? Author: Sajko, Tomislav / Rotim, Krešimir / Hećimović, Hrvoje. Publication: New Frontiers in Epilepsy. Functional and Peripheral Nerve Surgery. Keywords: Keywords in a foreign languages Temporal Lobe Epilepsy Treatment.Clinical and electrographic features, diagnosis and treatment. A practical guide to diagnosis and treatment. Van buren jm, marsan ca, mutsuga n: Dysphoric disorders and paroxysmal affects: Temporal lobe epilepsy (tle) is the most common form of focal (partial) epilepsy

Temporal lobe resection is the most common type of brain surgery used to treat people with epilepsy. The goal of temporal lobe resection surgery is to remove the seizure focus while preserving vital functions such as speech, sensation, movement, and memory. Temporal lobe resection may be performed alone or in conjunction with other surgeries. temporal lobe epilepsy treatment. Here, we report two patients treated with AH-DBS for drug-resistant temporal lobe epilepsy. The study was carried out with approval from the Ethics Committee of Beijing Sanbo Brain Hospital (Beijing, China) and according to the Declaration of Helsinki. Informed consent was obtained from all patients involved This study aimed to examine the close correlation between complicated febrile convulsions (CFC) and medial temporal lobe epilepsy and to delineate characteristics of temporal lobe epilepsy with CFC. Patients with temporal lobe epilepsy were divided into those with a prior episode of CFC (n=52), those with febrile convulsions other than CFC, and those witout either (n=345) Temporal lobe epilepsy (TLE) is a common and often refractory brain disease that is closely correlated with inflammation. Alpha-methyl-l-tryptophan (AMT) is recognized as a surrogate marker for epilepsy, characterized by high uptake in the epileptic focus. There are many advantages of using the magnetic targeting drug delivery system of superparamagnetic iron oxide nanoparticles (SPIONs) to. Temporal lobe epilepsy is the most common form of focal epilepsy. About 6 out of 10 people with focal epilepsy have temporal lobe epilepsy. Seizures in TLE start or involve in one or both temporal lobes in the brain. Contact Our Helpline. There are two types of TLE: Mesial temporal lobe epilepsy (MTLE) involves the medial or internal structures o

Seizure First Aid – EFEPA – Epilepsy Foundation Eastern

For temporal lobe epilepsy, surgery could potentially relieve seizure activity in more than 80 percent of patients. Epilepsy is a neurological disorder involving episodes of abnormal brain activity that cause seizures. Symptoms include staring spells, loss of consciousness, spells of confusion, and twitching or jerking movements in the arms and. Mesial temporal lobe epilepsy (MTLE) refers to a collection of syndromes with similar pathophysiology and clinical features, but with greater variation in prognosis and therefore treatment. The.

Temporal Lobe Damage: Potential Effects and Treatmen

Introduction. Temporal lobe epilepsy (TLE) is the most common subtype of epilepsy in human patients (Wiebe, 2000) that results in stereotyped pathological changes including a common aetiology of hippocampal sclerosis.TLE can be examined in an array of animal TLE models, unlike other human epilepsies (Kandratavicius et al., 2014; Levesque et al., 2016) treatment; partly because temporal lobe epilepsy may be the presenting symptom of some under-lying lesion such as a tumour, and partly because medical treatment presents particular problems ofits own. However,it is thebizarre formwhich these attacks may take that often leads to diffi-culties in diagnosis. Theattacks often take unusual forms. Temporal lobe epilepsy (TLE) is the most common type of partial onset epilepsy . Epilepsy has a severe impact on patients' quality of life, first, because patients experience unpredictable seizures that restrict them in activities of daily living and second, because patients can suffer from several neuropsychiatric comorbidities such as depression or cognitive decline Temporal lobe seizure experience. Hello everyone! I am new to this subreddit and new to epilepsy. I am having temporal lobe seizures and I'm currently taking Vimpat (150mg twice daily). Looking to see what others experience with these seizures, what are your triggers, and what medicine worked best for youso here's my story and experience. We compared medical treatment with surgical treatment of temporal-lobe epilepsy at the London Health Sciences Centre, University of Western Ontario, Canada, between July 1996 and August 2000

uniQure to Acquire Corlieve Therapeutics and Advance its Gene Therapy Program to Treat Temporal Lobe Epilepsy (TLE) June 22, 2021 11:31 ET | Source: uniQure Inc. uniQure Inc New strategies for the treatment of medically intractable epilepsy are desperately needed. Cell-based transplantation is slowly emerging as a real therapeutic possibility, although many barriers remain. Dr. Goldberg proposes to use specific, defined subtypes of cortical interneuron precursors to treat epilepsy and its comorbidities in an experimental model of acquired chronic temporal lobe.

Temporal Lobe Epilepsy Diagnosis & Treatment - NYC Columbia Neurosurgery in New York

  1. Gastaut 24-26,28 has also reviewed our present knowledge of the causes of temporal lobe epilepsy, and EEG Correlations With Pathological Changes in Temporal Lobe Epilepsy and their Significance in Surgical Treatment , in Temporal Lobe Epilepsy, M. Baldwin and P. Bailey, ed., Springfield, Ill: Charles C Thomas, Publishers, 1958,.
  2. Temporal lobe epilepsy is arguably the most common form of human epilepsy. It is certainly, by far, the most common form of epilepsy that we have seen in epilepsy centers where we operate, and it is the major focus of attention of basic scientists at this point. Recently, it has even become common to the lay public
  3. Abstract published in PubMed.gov . Objectives: To investigate the seizure outcome with medical treatment in patients with temporal lobe epilepsy (TLE) and its associated factors.We also investigated the social outcome of the patients. Methods: This was a retrospective study of a prospectively built electronic database of patients with epilepsy
  4. Epilepsy of the temporal lobe The brain is divided into sections called lobes - frontal, temporal, occipital and parietal. When the origin of recurrent crises can be traced back to the temporal lobe, we speak of epilepsy of the temporal lobe. Temporal lobe epilepsy can be caused by brain damage, such as traumatic damage or infection
  5. Sometimes, a temporal lobe seizure can become a grand mal seizure, in which the person loses consciousness and has convulsions. Temporal lobe epilepsy treatment options include medications, electrical brain stimulation, laser or other surgical approaches, and the ketogenic diet

Temporal Lobe Epilepsy: Symptoms, Causes and Treatment Life Person

Temporal lobe epilepsy (TLE) seizures begin in the temporal lobe and often involve unusual feelings, movements, or behaviors. A person can remain conscious or lose consciousness during a TLE attack. Possible causes of TLE include febrile seizures and some types of brain injury, but often the causes remain unknown Temporal lobe seizures cause behaviors such as smacking of the lips or rubbing the hands together. Other features of the seizures may include emotional or thought disturbances and hallucinations involving sounds, smells, or tastes. Treatment with medicine controls seizures in many people who have temporal lobe epilepsy Surgical Techniques for the Treatment of Temporal Lobe Epilepsy. Epilepsy Research and Treatment, 2012. Saleh Baeesa. Faisal Al Otaibi. Faisal Alotaibi. John Girvin. Saleh Baeesa. Faisal Al Otaibi. Faisal Alotaibi. John Girvin. Download PDF. Download Full PDF Package. This paper. A short summary of this paper Temporal Lobe Seizure. Verified By Apollo Neurologist. August 30, 2021. 0. 12. Temporal lobe seizures originate in the temporal lobes of your brain, responsible for emotions and short-term memory. The exact cause of temporal lobe seizure remains unknown. They are usually focal seizures with impaired awareness How Is Temporal Lobe Epilepsy Treated? Seizures in TLE usually get better with medicine. If medicines don't control the seizures, doctors may recommend neurostimulation (using a device to stimulate nerves to stop seizures) or surgery. The results from surgery are excellent, so neurologists prefer it over neurostimulation

Antidepressive treatment in patients with temporal lobe epilepsy and major depression

The benefit of tem- on magnetic resonance imaging and a REFERENCES poral lobectomy in treatment of refrac- predominance of focal seizures were 1 Jutila L, Immonen A, Mervaala E, et al. Long tory temporal lobe epilepsy has been term outcome of temporal lobe epilepsy positively associated with good outcome surgery: analyses of 140 consecutive patients. accepted for many years and a recent J. Abstract. Temporal lobe epilepsy (also called mesial temporal lobe epilepsy), the most frequent form of partial epilepsy in adults, is clinically characterized by alterations in consciousness combined by various functional manifestations including sensory, motor, psychic, and autonomic Epilepsy is among the most common neurologic disorders, affecting approximately 1% of the population. The most common seizure type in adults with medically intractable epilepsy is complex partial seizures, typically arising from the temporal lobe. Temporal lobectomy has been validated as a highly effective treatment for temporal lobe epilepsy Mesial temporal lobe epilepsy (MTLE) affects the inner part of the temporal lobe manifesting in the hippocampus, parahippocampal gyrus and the amygdala. MTLE is the most common type of epilepsy and is often characterized by the sense of an aura immediately preceding the seizure Temporal lobe epilepsy symptoms are a set of tell-tale symptoms indicative of seizures in the temporal lobe of the brain. People can experience a variety of symptoms during temporal lobe seizure activity, including confusion, hallucinations, a sense of anxiety, and purposeless movements not under the patient's control

temporal lobe epilepsy represents by far the most common form of focal epilepsy in adults, while it is one of the most common forms of epilepsy in children [ ]. Temporal lobe epilepsy usually presents with simple and/or complex partial seizures, although the underlying pathology may be any of Temporal lobe epilepsy ( TLE) is the most common of the localization-related . ›. Surgical treatment of epilepsy in adults. View in Chinese. Most centers use Wada tests only for patients with temporal lobe epilepsy at significant risk for cognitive decline (eg, left temporal lobe epilepsy with normal MRI, bilateral hippocampal atrophy. Surgery for temporal lobe epilepsy usually involves removing part of the temporal lobe. If you already had memory problems you might not notice it being worse after surgery. Language. The left temporal lobes are important for aspects of language. People with epilepsy sometimes struggle to find the word they are looking for

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What Is Temporal Lobe Epilepsy? Kids with temporal lobe epilepsy (TLE) have seizures that start in one of the temporal lobes of the brain.The temporal lobes are on the sides of the brain behind the temples. This area of the brain is involved in controlling emotions and short-term memory. TLE begins in children around 10 years old to late adolescence, but can start at any age if there is a. Temporal lobe epilepsy surgery is one of the most effective types of epilepsy surgery, with most people going on to have long-term freedom from seizures. However, if temporal lobe surgery takes place in the side of the brain used for language, it can cause some impairment, particularly to word-finding, in about a third of individuals A clinical feature differentiating medial from neocortical temporal lobe epilepsy. Arch Neurol 56: 927 - 932, 1999 Dupont S, Semah F, Boon P, et al: Association of ipsilateral motor automatisms and contralateral dystonic posturing. A clinical feature differentiating medial from neocortical temporal lobe epilepsy. Arch Neurol 56: 927-932, 199 Temporal lobe epilepsy can be treated with medicines that are used for epilepsy but treatment will also depend on any underlying temporal lobe lesion. See separate leaflet called Epilepsy with Focal Seizures for more details Although the first description of familial mesial temporal lobe epilepsy defined it as a benign condition (14; 16), it is now well-known that some patients may be refractory to medical treatment. Overall, 81% of familial mesial temporal lobe epilepsy patients achieved good seizure control on medication or remitted spontaneously